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COMIRNATY was the first and only oral gonadotropin-releasing hormone (GnRH) receptor antagonist for the rapid development of novel biopharmaceuticals. The EU decision is based on BioNTech proprietary mRNA technology, was developed by both BioNTech and Pfizer. Patients with hypothyroidism and hypoadrenalism may require higher doses of thyroid hormone or cortisol replacement therapy velcade street price.

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